www/content/topics/research-area-a/_index.md
Michael Hanke 038b0c9562
Remove the "Area-X" labels from the research topics
They are meaningless for an outside reader, and just an
aspect of the TRR project structure. This is also where
the label remains.
2024-06-21 07:15:44 +02:00

22 lines
1.3 KiB
Markdown

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title: Negative valence system
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The negative valence system is primarily responsible for reactions to aversive
situations and includes the constructs of acute threat, potential threat,
sustained threat, as well as loss and frustrative non-reward. The acute threat
system is related to the defensive motivational system, which protects the
organism from a perceived danger initiating adaptive responses. The frustrative
non-reward system is triggered by the withdrawal or prevention of expected
rewards, which may lead to an arousal exceeding normal regulatory capacity and
thus precipitating aggressive or antisocial responses.
We hypothesize that a perceived or potential danger can trigger a fight
response in individuals hypersensitive to threat. Similarly, aggressive
behavior may be a response to frustration. Anger in response to frustrative
non-reward can promote aggressive behaviors. Investigations of this topic will
address whether the aggressive response is determined by increased and altered
bottom-up signaling of threat cues and/or frustrative non-reward, and how this
is reflected on the neural, neurochemical, and hormonal levels. The focus is on the identification of specific negative valence system dysfunctions relevant to aggression in mental disorders.
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